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Our solutions

Leveraging precision-cut tissue slices (PCTS), we help drug developers generate human-relevant evidence, increasing preclinical decision confidence and reducing translational uncertainty.

Don’t approximate human biology, test it

Surrogate models fail to produce reliable data. In-vitro cell cultures and organoids fail to recreate tissue complexity and therapeutic responses in animal models are rarely replicated in the clinic.

Human tissue provides a more translatable platform to understand therapeutic response in real human disease.

FibroFind’s PCTS platform bridges the gap by enabling studies in viable, intact human tissue, supporting translational confidence, portfolio prioritisation and earlier go or no-go decisions.

Target identification and validation

Interrogate novel therapeutic targets in intact, viable human tissue to build the real biological evidence needed to support confident early decisions.

Lead screening and optimization

Test and rank novel interventions early to generate the decision-grade data needed to prioritise stronger candidates and reduce preclinical risk.

Pharmacology

Gain direct evidence of target engagement in intact human tissue to strengthen the translational case behind your program and support IND-enabling submissions.

Drug safety

Assess tissue viability and emerging safety signals in intact human tissue to identify weak assets early and avoid unnecessary progression into formal GLP studies.

Make your next decision with confidence

Find out how we replace biological guesswork with clarity, giving high-potential assets the best chance to reach patients.

The new standard

Combining the benefits of ex-vivo PCTS and our proprietary bioreactor technology, our platform generates credible, human-relevant evidence to de-risk your drug discovery and development to support stronger preclinical decisions.

Tissue bioreactor technology

Proprietary bioreactor systems designed to preserve native tissue structure and function, enabling controlled, extended study in living human tissue.

Tissue types and indications

Ethical procurement of viable human liver, lung and kidney tissue through established clinical partnerships for use in our PCTS platforms.

Because attrition costs

With fewer than 10% of drug candidates reaching approval, every preclinical decision carries significant capital and reputational consequences. Advancing the wrong asset on the basis of uncertain data compounds that risk substantially.

Rather than relying on simplified cell culture systems or costly animal models, our bioreactor-supported PCTS platform enables drug response to be studied directly in viable, intact human tissue.

We help underpin your strategy with the defensible, human-relevant evidence required to protect asset valuation, drive capital efficiency and secure project funding.

Related resources

Explore how FibroFind’s solutions help drug developers increase confidence in preclinical decision-making using intact, viable human tissue with disease present.

News

FibroFind appoints leading transplant physician Professor Andrew Fisher as Chief Medical Officer

FibroFind appoints Professor Andrew Fisher as Chief Medical Officer as the company continues its global expansion.

Poster

Combination of an Acetyl-Coenzyme A Carboxylase Inhibitor and Fibroblast Growth Factor-19 Reduced Tissue Triglyceride Content and Fibrosis in Human Precision-Cut Liver Slices

See how combining ACC inhibition with FGF19 reduced triglyceride accumulation and fibrosis in human precision-cut liver slices.

News

FibroFind appoints new CEO to lead firm through next phase of growth

FibroFind appoints co-founder Lee Borthwick as CEO to lead its next phase of growth and scale its human-relevant preclinical testing platform.

The evidence your program demands

Speak to our team about your program.