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FibroFind appoints leading transplant physician Professor Andrew Fisher as Chief Medical Officer

FibroFind appoints Professor Andrew Fisher as Chief Medical Officer as the company continues its global expansion.

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Poster

Combination of an Acetyl-Coenzyme A Carboxylase Inhibitor and Fibroblast Growth Factor-19 Reduced Tissue Triglyceride Content and Fibrosis in Human Precision-Cut Liver Slices

See how combining ACC inhibition with FGF19 reduced triglyceride accumulation and fibrosis in human precision-cut liver slices.

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FibroFind appoints new CEO to lead firm through next phase of growth

FibroFind appoints co-founder Lee Borthwick as CEO to lead its next phase of growth and scale its human-relevant preclinical testing platform.

Scientific article

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ

Explore how hepatocellular senescence spreads to distant organs via TGFβ signalling, contributing to multi-organ dysfunction in severe acute liver disease.

Scientific article

A Mammalian Target of Rapamycin- Perilipin 3 (mTORC1-Plin3) Pathway is Essential to Activate Lipophagy and Protects Against Hepatosteatosis

Discover how the mTORC1–Plin3 pathway activates hepatic lipophagy, promoting lipid droplet degradation and protecting against hepatosteatosis.

Scientific article

Neutrophils Induce Paracrine Telomere Dysfunction and Senescence in ROS‐Dependent Manner

Understand how neutrophil-derived ROS drive telomere dysfunction and cellular senescence, revealing a mechanism for spread of senescence.

Scientific article

c-Rel Orchestrates Energy-Dependent Epithelial and Macrophage Reprogramming in Fibrosis

Learn how the c-Rel–Pfkfb3 axis reprograms hepatocyte and macrophage metabolism to drive paracrine signalling and fibrosis.

Scientific article

A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices

This landmark publication introduces our bioreactor technology for modelling liver fibrosis and testing antifibrotic therapies in human and rodent PCLSs.